N,N-DIMETHYLFORMAMIDE (CAS No. 68-12-2)

NTP technical report on the toxicity studies of N,N-Dimethylformamide (CAS No. 68-12-2) Administered by Inhalation to F344/N Rats and B6C3F1 Mice.

N,N-Dimethylformamide (DMF), a colorless liquid with a high boiling point, is a solvent used in a large number of industrial processes. Male and female F344/N rats (30/sex/group) and B6C3F1 mice (10/sex/group) were exposed to DMF vapors at concentrations of 0, 50, 100, 200, 400, or 800 ppm, 6 hours/day, 5 days/week, for 13 weeks in whole body exposure inhalation studies. In addition to histopat...

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specific example of “a world aswarm with viral zoonoses”), anthrax, smallpox, brucellosis, botulism, and ricin. Information is also provided on genetically-engineered protein toxins, as well as genetic fingerprinting for forensic studies and the use of genomics for the agents of tularemia, brucellosis, and clostridial gas gangrene. Notably, several chapters are devoted to critical topics that a...

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